Fold Increase Calculator

Fold Increase Calculator

Enter the initial value and final value from your measurement or experiment. The calculator determines the fold change between these values. For percentage display, toggle the results format using the switch.

  • Inputs: Initial = 100, Final = 300
  • Process: Enter both values
  • Result: 3-fold increase (300% change)

Fold Increase Calculation Chart

ExampleInitial ValueFinal ValueCalculationFold Increase
Population Growth1,0005,000(5000 / 1000) = 55
Investment Growth2,0008,000(8000 / 2000) = 44
Bacterial Amplification500 cells4,000 cells(4000 / 500) = 88
Sales Growth200 units1,000 units(1000 / 200) = 55
Protein Concentration0.1 mg/mL0.8 mg/mL(0.8 / 0.1) = 88

How to Calculate Fold Increase

To find the fold increase, divide your final value by the initial value. A result greater than 1 indicates an increase, while less than 1 shows a decrease. For a percent change, subtract 1 from the fold change and multiply by 100.

  • Inputs: Cell count increased from 5,000 to 20,000
  • Calculations: 20,000 ÷ 5,000 = 4
  • Result: 4-fold increase

Fold Increase Formula

Fold Increase = Final Value ÷ Initial Value
Percent Change = (Fold Increase - 1) × 100

Where:
Final Value = Ending measurement
Initial Value = Starting measurement

Gene Expression

  • Inputs: Initial = 100 copies, Final = 800 copies
  • Calculations: 800 ÷ 100
  • Result: 8-fold increase

Cell Growth

  • Inputs: Initial = 1,000 cells, Final = 4,000 cells
  • Calculations: 4,000 ÷ 1,000
  • Result: 4-fold increase

Protein Level

  • Inputs: Initial = 50 units, Final = 300 units
  • Calculations: 300 ÷ 50
  • Result: 6-fold increase

Enzyme Activity

  • Inputs: Initial = 25 units, Final = 125 units
  • Calculations: 125 ÷ 25
  • Result: 5-fold increase

Population Growth

  • Inputs: Initial = 200, Final = 1,400
  • Calculations: 1,400 ÷ 200
  • Result: 7-fold increase

What is Fold Increase?

Fold increase measures relative change between two values, showing how many times larger the final value is compared to the initial value. Used extensively in scientific research, particularly in biology and biochemistry, to quantify changes in measurements over time or between conditions.

2-fold = Double the initial value
3-fold = Triple the initial value
0.5-fold = Half the initial value

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